Does Vaping Lead to Increased Risk of Bladder Cancer?

Some recent studies claim that vaping might lead to increased bladder cancer risk as well as higher risk of mortality for bladder cancer patients.

This data was presented at the 112th Annual Scientific Meeting of the American Urological Association earlier this month, which talks about how smoking is a clear cause of bladder cancer, although risk of vaping has yet to be determined.

This data took into account three different studies.

Smoking Intensity Predicts Survival in Bladder Cancer Patients

The first study reviewed data from a study collected from 1981 to 2009. This study showed that smoking more packs per day increases risk of death in patients with bladder cancer while smoking less than 1-2 packs per day significantly reduces risk.

My Thoughts

I have no idea what the researchers were thinking when they translated this data to vapers. Vaping isn’t anything like smoking and the results of this study is not at all relevant.

Bladder Carcinogens In Urine of E-Cig Users

The second study consisted of testing the urine of 13 electronic cigarette users and 10 non-users for five known bladder carcinogens.

What the researchers found was that 92% of the e-cig users tested positive for two of the five cancer causing compounds that they were looking for.

My Thoughts

There are some pretty big things missing from this research. For one, the sample size is extremely low. And how many of these e-cig users are dual users? And how long has it been since these participants last smoked a cigarette? And what products were these people using? And how were these compounds formed in the vapor? I also don’t know what methods were used of if vaping product were provided to the participants.

Something interesting that Dr. Farsalinos also pointed out in regards to this study is that previous research on the two cancer-causing compounds the researchers found is entirely dependent on environments. Both o-toluidine and 2-naphthylamine have been found in other studies to exist in the same amounts in smokers as it does in non-smokers, which is because humans can uptake these chemicals from their environments. Dr. Farsalinos says this is why these two biomarkers not always used to measure toxin exposure from cigarette smoke.

What the researchers should have done is test the aerosol for these compounds, not the urine of the participants.

Vapor Results in Tumor-Inducing DNA Damage

And finally, they showed data from a study that showed e-cigarette vapor inducing DNA damage in the bladder.

Their results showed that vapor causes tumor-inducing DNA damage in the bladder membrane.

They also found that nicotine, nitrosamine, and formaldehyde cause the same damage in bladder cells and inhibit DNA repair. They also say that nicotine can be nitrosatized in cells, which would metabolize into carcinogenic nitrosamines and formaldehyde.

My Thoughts

The problem with this last part is that they tested nicotine on cells. That’s not the same way nicotine comes into contact with our cells from vaping. You can also look at research on smokeless tobacco like chew and snus, which shows that it’s not associated with risk of bladder cancer. So if chew, which has nicotine, is not linked to bladder cancer risk, why would the nicotine in electronic cigarettes?

And the formaldehyde scare has already been debunked. Large amounts of formaldehyde is only formed from burnt wicks. And formaldehyde is also produced naturally by our bodies and is found naturally in many foods we eat, such as fruits, vegetables, and fish.

These Studies Are Useless

There’s clearly tons of misleading information in these studies and in the researcher’s conclusions, but when you look into the data, you see that there’s actually nothing conclusive or convincing here.

Proposed Vape Regulations Throughout the U.S.

There’s always something to fight. Protect your right to vape by taking action against proposed regulations in your city or state. Visit to find more information and for instructions in participating in call-to-actions.

San Francisco

San Francisco Supervisor, Malia Cohen has introduced a flavor ban for both flavored tobacco and vapor products. CASAA is saying that the first hearing MIGHT happen on Wed. May 24th at 10:30 am. If you live in San Francisco, reach out to city supervisors and tell them to oppose the ordinance.

Los Angeles

LA has bill HB 271 which would raise the tax on e-juice from $0.05 per ML to $0.13 per ML. It was actually heard last week and the committee agreed to put this bill on hold while they further study if/how vapor products help smokers quit smoking and how other states are taxing e-liquids. So it’s a temporary win for now, but the bill is still there, so keep an eye on it and voice your opinions.

New York

NY state has two bills in progress. One bill is designed to ban vaping indoors and the other bill is designed to raise the age of buying vaping products to 21. If you live in NY, contact your state senators and ask them to oppose these bills.

New York City

NYC also has an ordinance that would require vape shops to have licenses to sell vapor products. The big issue with this bill is that licenses will only be issued for 90 days after the bill passes, then no more licenses will be given out. That means any shop that doesn’t obtain a license in time will be forced to shut down and it also means that no new vape shops will be able to open.


Maryland’s HB 523 proposes imposing licensing regulations on Maryland vapor business which now includes a last minute partial online sales ban. Manufacturers are still allowed to sell online, but distributors and local shops are not allowed to sell online. The bill has already passed the house and senate and the last step is for it to be signed into law, so the only thing you can do now is request that Maryland’s Governor Larry Hogan VETO the bill.

You can find more information about all of these bills and ordinances on along with information on who you need to contact and what you can say.

The Latest Vaping News – The VapePassion Show Episode 70

Some of the topics discussed include:

  • E-Juice Review: Mangoer Boba from OGNL BOBA
  • Proposed Regulations Throughout the U.S.
  • Does Vaping Lead to Increased Risk of Bladder Cancer?
  • The Navy Has Developed a Safer Alternative To Lithium-Ion Batteries
  • Dr. Gottlieb Takes Over as FDA Commissioner and Addresses His Staff

Continue reading The Latest Vaping News – The VapePassion Show Episode 70

The Latest Vaping News – The VapePassion Show Episode 69

Some of the topics discussed include:

  • E-Juice Review: Glazed Donuts by Loaded E-Liquid
  • Jai Haze Vs Mike Vapes: Jai’s Perspective
  • Vape Reviewers That Don’t Cuss
  • A Sheriff Gets Prison Time For Selling E-Cigarettes to Inmates
  • Tobacco Control Journal Caught Hiding Sample Size To Falsely Claim That Vaping Is a Gateway to Smoking
  • Does Pre-Made E-Juice Need to Steep Again After Adding More Nicotine?

Continue reading The Latest Vaping News – The VapePassion Show Episode 69

The Latest Vaping News – The VapePassion Show Episode 68

Some of the topics discussed include:

  • The Cole-Bishop Bill Didn’t Make Into to the 2017 US Budget
  • The FDA Has Delayed Compliance Deadlines by Three Months
  • Could a Small Town in Wisconsin Save the Vaping Industry?
  • Is it Unethical To Buy Vape Products Released After the Deeming Date?
  • New Study Shows Vaping Doesn’t Promote Cancer Growth

Continue reading The Latest Vaping News – The VapePassion Show Episode 68

Let's Vape!